Context
This experiment, examines motor planning and control. MEG data is recorded while subjects move a cursor on screen with help of a joystick. Various motion parameters are manipulated on screen so as to examine the dynamics of motor control.
Technology
This experiment uses
- MEG (306 sensors)
- eye tracking (x,y position)
- joystick 2D position (x,y position)
Pipeline
MEG and eye tracker data are merged "out of the box". The raw input is thus a .fif file with 308 data channels (306 MEG + x & y eye position).
The joystick data is inserted. Evoked fields are computed by condition. An anatomical MRI is used to model sources using minimum norm estimate in Brainstorm. Time-frequency source estimates are computed in FieldTrip (using DICS). ANOVAs are used to highlight ROIs. Connectivity between ROIs is estimated with imaginary coherence. Statistical inference is drawn using MEGanova.
Preprocessing
| Operation | Input format | Software | Output format | Comment / Link | |
|---|---|---|---|---|---|
| 1 | Merge joystick and MEG | .fif | dataHandler -merge | .fif | data with MEG, eye tracker, joystick. Datahandler |
| 2 | Maxfilter | .fif | maxfilter | .fif | maxfilter |
| 3 | Detect saccades | .fif | FieldTrip | .fif | Ask script to Former user (Deleted) |
| 4 | Mark bad data segments | .fif | Muse | .fif | Review data with Muse |
| 5 | Manipulate markers to create conditions | .fif | dataHandler -adm | .fif |
|
| 6 | Run ICA and reject blink and cardiac components | .fif | FieldTrip and custom script | .fif | Blink and cardiac artifact scripts |
| 7 | Create Evoked fields | .fif | dataHandler -sync -rbp | .fif |
|
| Operation | Input format | Software | Output format | Comment / Link |
|---|---|---|---|---|---|
| 1 | Segment T1 MRI | .dic or other | recon-all (Freesurfer) | freesurfer folder |
|
| 2 | Import MEG and structural in Brainstorm | Brainstorm supported types | Brainstorm | Brainstorm internal |
|
| 3 | Minimum norm estimate | Brainstorm internal | Brainstorm | Brainstorm internal | See tutorials 20 and following of the Brainstorm tutorials |
| 4 | Project sources on template | Brainstorm internal | Brainstorm | Brainstorm internal | |
| 5 | Temporal averages | Brainstorm internal | Brainstorm? | Brainstorm internal? | ask Former user (Deleted) how he did it |
| 6 | ROI design with statistics | Brainstorm internal | MegAnova | Brainstorm internal |
|
| 7 |
FieldTrip source space time-frequency analysis
| Operation | Input format | Software | Output format | Comment / Link | |
|---|---|---|---|---|---|
| 1 | Import fif into FieldTrip | .fif | FieldTrip | FieldTrip .mat | Import .fif into FieldTrip |
| 2 | Run DICS source reconstruction | (any) | FieldTrip | FieldTrip .mat | Localizing oscillatory sources using beamformer techniques |
| 3 | Run ANOVAs on TF windows of interest | FieldTrip .mat | MegAnova | ??? | Using Meganova to run ANOVAs |
| 4 | Compute ROI imaginary coherence | FieldTrip .mat | FieldTrip | FieldTrip.mat | Causality analysis in FieldTrip |
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http://www.fieldtriptoolbox.org/tutorial/beamformer
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